Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.74	9.88	-13.1	2	5	0	63	387.361	6	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	4.74	9.66	-33.2	3	5	1	64	388.369	6	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
PPIA-1-E	Cyclophilin A (cluster #1 Of 2), Eukaryotic	Eukaryotes	499	0.32	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
PPIA_HUMAN	P62937	Cyclophilin A, Human	499	0.32	Binding ≤ 1μM
PPIA_HUMAN	P62937	Cyclophilin A, Human	499	0.32	Binding ≤ 10μM

Description	Species
APOBEC3G mediated resistance to HIV-1 infection	Homo sapiens (PPIA_HUMAN)
Assembly Of The HIV Virion	Homo sapiens (PPIA_HUMAN)
Basigin interactions	Homo sapiens (PPIA_HUMAN)
Binding and entry of HIV virion	Homo sapiens (PPIA_HUMAN)
Budding and maturation of HIV virion	Homo sapiens (PPIA_HUMAN)
Early Phase of HIV Life Cycle	Homo sapiens (PPIA_HUMAN)
Integration of provirus	Homo sapiens (PPIA_HUMAN)
Minus-strand DNA synthesis	Homo sapiens (PPIA_HUMAN)
Platelet degranulation	Homo sapiens (PPIA_HUMAN)
Plus-strand DNA synthesis	Homo sapiens (PPIA_HUMAN)
Uncoating of the HIV Virion	Homo sapiens (PPIA_HUMAN)