| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 23rd, 2008 | 25 | Yes |
Popular Name: N-[1-[(3-phenoxyphenyl)methyl]-4-piperidyl]propanamide N-[1-[(3-phenoxyphenyl)methyl]-4…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.85 | 10.38 | -46.59 | 2 | 4 | 1 | 43 | 339.459 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CCR8-1-E | C-C Chemokine Receptor Type 8 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 9200 | 0.28 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CCR8_HUMAN | P51685 | C-C Chemokine Receptor Type 8, Human | 9200 | 0.28 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Chemokine receptors bind chemokines | |
| G alpha (i) signalling events |
