| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 23rd, 2008 | 31 | No |
Popular Name: (E)-N-(2,5-diphenylpyrazol-3-yl)-3-(4-nitrophenyl)prop-2-enamide (E)-N-(2,5-diphenylpyrazol-3-yl)…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.95 | 14.22 | -18.35 | 1 | 7 | 0 | 93 | 410.433 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM5-2-E | Metabotropic Glutamate Receptor 5 (cluster #2 Of 5), Eukaryotic | Eukaryotes | 560 | 0.28 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM5_RAT | P31424 | Metabotropic Glutamate Receptor 5, Rat | 560 | 0.28 | Binding ≤ 1μM |
| GRM5_RAT | P31424 | Metabotropic Glutamate Receptor 5, Rat | 1810 | 0.26 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | |
| G alpha (q) signalling events |
