| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 23rd, 2008 | 29 | Yes |
Popular Name: 2,2-diphenyl-1-[4-[(1S)-1-(3-pyridyl)ethyl]piperazin-1-yl]ethanone 2,2-diphenyl-1-[4-[(1S)-1-(3-pyr…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.47 | 10.57 | -9.57 | 0 | 4 | 0 | 36 | 385.511 | 5 | ↓ |
| Lo Low (pH 4.5-6) | 3.47 | 12.8 | -113.59 | 2 | 4 | 2 | 39 | 387.527 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PTAFR-3-E | Platelet Activating Factor Receptor (cluster #3 Of 3), Eukaryotic | Eukaryotes | 1200 | 0.29 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PTAFR_HUMAN | P25105 | Platelet Activating Factor Receptor, Human | 1200 | 0.29 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Class A/1 (Rhodopsin-like receptors) | |
| G alpha (q) signalling events | |
| Interferon gamma signaling |
