| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 24th, 2008 | 23 | Yes |
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.58 | 7.08 | -124.33 | 12 | 7 | 3 | 144 | 330.545 | 18 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DHYS-1-E | Deoxyhypusine Synthase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 80 | 0.43 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DHYS_RAT | Q6AY53 | Deoxyhypusine Synthase, Rat | 80 | 0.43 | Binding ≤ 1μM |
| DHYS_RAT | Q6AY53 | Deoxyhypusine Synthase, Rat | 80 | 0.43 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Hypusine synthesis from eIF5A-lysine |
