| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 25th, 2008 | 28 | Yes |
Popular Name: 4-chloro-N-[4-(3,4-dihydro-2H-quinoline-1-carbonyl)phenyl]benzamide 4-chloro-N-[4-(3,4-dihydro-2H-qu…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.15 | 11.34 | -14.2 | 1 | 4 | 0 | 49 | 390.87 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| V1AR-1-E | Vasopressin V1a Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5100 | 0.26 | Binding ≤ 10μM |
| V2R-1-E | Vasopressin V2 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1900 | 0.29 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| V1AR_RAT | P30560 | Vasopressin V1a Receptor, Rat | 5100 | 0.26 | Binding ≤ 10μM |
| V2R_RAT | Q00788 | Vasopressin V2 Receptor, Rat | 1900 | 0.29 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| G alpha (s) signalling events | |
| Vasopressin regulates renal water homeostasis via Aquaporins | |
| Vasopressin-like receptors |
