| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 25th, 2008 | 29 | Yes |
Popular Name: 3,5-dichloro-N-[4-(3,4-dihydro-2H-quinoline-1-carbonyl)phenyl]benzamide 3,5-dichloro-N-[4-(3,4-dihydro-2…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.76 | 11.84 | -13.15 | 1 | 4 | 0 | 49 | 425.315 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| V1AR-1-E | Vasopressin V1a Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 9400 | 0.24 | Binding ≤ 10μM |
| V2R-1-E | Vasopressin V2 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 82 | 0.34 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| V2R_RAT | Q00788 | Vasopressin V2 Receptor, Rat | 82 | 0.34 | Binding ≤ 1μM |
| V1AR_RAT | P30560 | Vasopressin V1a Receptor, Rat | 9400 | 0.24 | Binding ≤ 10μM |
| V2R_RAT | Q00788 | Vasopressin V2 Receptor, Rat | 82 | 0.34 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| G alpha (s) signalling events | |
| Vasopressin regulates renal water homeostasis via Aquaporins | |
| Vasopressin-like receptors |
