| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 25th, 2008 | 29 | No |
Popular Name: (5Z)-2,2,4-trimethyl-5-(p-tolylmethylene)-1H-chromeno[3,4-f]quinoline (5Z)-2,2,4-trimethyl-5-(p-tolylm…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 6.91 | 14.28 | -8.62 | 1 | 2 | 0 | 25 | 379.503 | 1 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PRGR-2-E | Progesterone Receptor (cluster #2 Of 3), Eukaryotic | Eukaryotes | 70 | 0.35 | Binding ≤ 10μM |
| Z80110-1-O | CV-1 (Kidney Cells) (cluster #1 Of 2), Other | Other | 590 | 0.30 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PRGR_HUMAN | P06401 | Progesterone Receptor, Human | 70 | 0.35 | Binding ≤ 1μM |
| PRGR_HUMAN | P06401 | Progesterone Receptor, Human | 70 | 0.35 | Binding ≤ 10μM |
| Z80110 | Z80110 | CV-1 (Kidney Cells) | 590 | 0.30 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Nuclear Receptor transcription pathway | |
| Nuclear signaling by ERBB4 |
