| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 25th, 2008 | 31 | Yes |
Popular Name: methyl methyl
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.84 | 10.56 | -44.03 | 4 | 7 | 1 | 97 | 421.521 | 10 | ↓ |
| Mid Mid (pH 6-8) | 3.84 | 10.56 | -16.42 | 3 | 7 | 0 | 96 | 420.513 | 10 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FNTA-1-E | Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #1 Of 2), Eukaryotic | Eukaryotes | 10000 | 0.23 | Functional ≤ 10μM |
| PGTB1-1-E | Geranylgeranyl Transferase Type I Beta Subunit (cluster #1 Of 1), Eukaryotic | Eukaryotes | 10000 | 0.23 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PGTB1_MOUSE | Q8BUY9 | Geranylgeranyl Transferase Type I Beta Subunit, Mouse | 10000 | 0.23 | Functional ≤ 10μM |
| FNTA_MOUSE | Q61239 | Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Mouse | 10000 | 0.23 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Apoptotic cleavage of cellular proteins | |
| Inactivation, recovery and regulation of the phototransduction cascade |
