In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
June 25th, 2008 | 35 | Yes |
Popular Name: methyl methyl
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 5.00 | 13.1 | -51.39 | 4 | 7 | 1 | 97 | 471.581 | 10 | ↓ |
Mid Mid (pH 6-8) | 5.00 | 12.59 | -17.86 | 3 | 7 | 0 | 96 | 470.573 | 10 | ↓ |
Mid Mid (pH 6-8) | 5.00 | 12.27 | -14.04 | 3 | 7 | 0 | 96 | 470.573 | 10 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
FNTA-1-E | Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #1 Of 2), Eukaryotic | Eukaryotes | 500 | 0.25 | Functional ≤ 10μM |
PGTB1-1-E | Geranylgeranyl Transferase Type I Beta Subunit (cluster #1 Of 1), Eukaryotic | Eukaryotes | 500 | 0.25 | Functional ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
PGTB1_MOUSE | Q8BUY9 | Geranylgeranyl Transferase Type I Beta Subunit, Mouse | 500 | 0.25 | Functional ≤ 10μM |
FNTA_MOUSE | Q61239 | Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Mouse | 500 | 0.25 | Functional ≤ 10μM |
Description | Species |
---|---|
Apoptotic cleavage of cellular proteins | |
Inactivation, recovery and regulation of the phototransduction cascade |