In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
June 25th, 2008 | 28 | No |
Popular Name: (5S)-5-(4-chlorophenyl)-2,2-dimethyl-4-methylene-3,5-dihydro-1H-chromeno[3,4-f]quinoline (5S)-5-(4-chlorophenyl)-2,2-dime…
None
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 6.84 | 12.05 | -7.73 | 1 | 2 | 0 | 21 | 387.91 | 1 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
PRGR-1-E | Progesterone Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1755 | 0.29 | Functional ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
PRGR_HUMAN | P06401 | Progesterone Receptor, Human | 124 | 0.35 | Functional ≤ 10μM |
Description | Species |
---|---|
Nuclear Receptor transcription pathway | |
Nuclear signaling by ERBB4 |