| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 26th, 2008 | 35 | Yes |
Popular Name: 2-[3-[(2-chlorophenyl)-methyl-BLAHyl]prop-2-ynyl]-3,4-dihydroisoquinolin-1-one 2-[3-[(2-chlorophenyl)-methyl-BL…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.26 | 14.35 | -19.86 | 0 | 6 | 0 | 63 | 498.011 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PTAFR-2-E | Platelet Activating Factor Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 5 | 0.33 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PTAFR_HUMAN | P25105 | Platelet Activating Factor Receptor, Human | 5 | 0.33 | Binding ≤ 1μM |
| PTAFR_HUMAN | P25105 | Platelet Activating Factor Receptor, Human | 5 | 0.33 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Class A/1 (Rhodopsin-like receptors) | |
| G alpha (q) signalling events | |
| Interferon gamma signaling |
