| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 26th, 2008 | 22 | Yes |
Popular Name: 2-[2-(4-bromophenyl)imidazo[5,4-b]pyridin-3-yl]-N,N-dimethyl-acetamide 2-[2-(4-bromophenyl)imidazo[5,4-…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.43 | 8.59 | -16.35 | 0 | 5 | 0 | 51 | 359.227 | 3 | ↓ |
| Lo Low (pH 4.5-6) | 2.43 | 8.85 | -40.28 | 1 | 5 | 1 | 52 | 360.235 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z104301-1-O | GABA-A Receptor; Anion Channel (cluster #1 Of 8), Other | Other | 3000 | 0.35 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z104301 | Z104301 | GABA-A Receptor; Anion Channel | 3000 | 0.35 | Binding ≤ 10μM |
