| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 26th, 2008 | 26 | Yes |
Popular Name: N-(2-acetamidoethyl)-2-[2-(4-chlorophenyl)imidazo[5,4-b]pyridin-3-yl]acetamide N-(2-acetamidoethyl)-2-[2-(4-chl…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.64 | 5.75 | -20.48 | 2 | 7 | 0 | 89 | 371.828 | 6 | ↓ |
| Lo Low (pH 4.5-6) | 1.64 | 6.01 | -46.91 | 3 | 7 | 1 | 90 | 372.836 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z104301-1-O | GABA-A Receptor; Anion Channel (cluster #1 Of 8), Other | Other | 7200 | 0.28 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z104301 | Z104301 | GABA-A Receptor; Anion Channel | 7200 | 0.28 | Binding ≤ 10μM |
