Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.11	12.92	-112.39	0	6	-2	98	436.533	10	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	5.11	13.36	-105.68	1	6	-1	99	437.541	10	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
AGTR2-1-E	Angiotensin II Type 2 (AT-2) Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	34	0.34	Binding ≤ 10μM
AGTRA-1-E	Angiotensin II Type 1a (AT-1a) Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	34	0.34	Binding ≤ 10μM
AGTRB-1-E	Angiotensin II Type 1b (AT-1b) Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	34	0.34	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
AGTRA_RAT	P25095	Angiotensin II Type 1a (AT-1a) Receptor, Rat	33.6	0.34	Binding ≤ 1μM
AGTRB_RAT	P29089	Angiotensin II Type 1b (AT-1b) Receptor, Rat	33.6	0.34	Binding ≤ 1μM
AGTR2_RAT	P35351	Angiotensin II Type 2 (AT-2) Receptor, Rat	33.6	0.34	Binding ≤ 1μM
AGTRA_RAT	P25095	Angiotensin II Type 1a (AT-1a) Receptor, Rat	33.6	0.34	Binding ≤ 10μM
AGTRB_RAT	P29089	Angiotensin II Type 1b (AT-1b) Receptor, Rat	33.6	0.34	Binding ≤ 10μM
AGTR2_RAT	P35351	Angiotensin II Type 2 (AT-2) Receptor, Rat	33.6	0.34	Binding ≤ 10μM

Description	Species
G alpha (i) signalling events	Rattus norvegicus (AGTR2_RAT)
G alpha (q) signalling events	Rattus norvegicus (AGTRA_RAT)
Peptide ligand-binding receptors	Rattus norvegicus (AGTRA_RAT)