| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 27th, 2008 | 27 | Yes |
Popular Name: 1-[(1S)-2-cyclohexyl-1-methyl-ethyl]-1-methyl-3-(4-phenoxyphenyl)urea 1-[(1S)-2-cyclohexyl-1-methyl-et…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 6.52 | 12.99 | -9.93 | 1 | 4 | 0 | 42 | 366.505 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| NPY5R-2-E | Neuropeptide Y Receptor Type 5 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 71 | 0.37 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| NPY5R_HUMAN | Q15761 | Neuropeptide Y Receptor Type 5, Human | 71 | 0.37 | Binding ≤ 1μM |
| NPY5R_HUMAN | Q15761 | Neuropeptide Y Receptor Type 5, Human | 71 | 0.37 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| Peptide ligand-binding receptors |
