| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 27th, 2008 | 34 | Yes |
Popular Name: 4-tert-butyl-N-[6-(2-methoxyethoxy)-5-(3-methoxyphenoxy)pyrimidin-4-yl]benzenesulfonamide 4-tert-butyl-N-[6-(2-methoxyetho…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.61 | 7.3 | -54.2 | 0 | 9 | -1 | 111 | 486.57 | 11 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| EDNRA-3-E | Endothelin Receptor ET-A (cluster #3 Of 3), Eukaryotic | Eukaryotes | 92 | 0.29 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| EDNRA_PIG | Q29010 | Endothelin Receptor ET-A, Pig | 92 | 0.29 | Binding ≤ 1μM |
| EDNRA_PIG | Q29010 | Endothelin Receptor ET-A, Pig | 92 | 0.29 | Binding ≤ 10μM |
