| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 27th, 2008 | 21 | Yes |
Popular Name: N-[(3R,4S)-6-fluoro-3-hydroxy-2,2-dimethyl-chroman-4-yl]-N-methyl-ethanesulfonamide N-[(3R,4S)-6-fluoro-3-hydroxy-2,…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.85 | 1.97 | -13.21 | 1 | 5 | 0 | 67 | 317.382 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KCNE1-1-E | Voltage-gated Potassium Channel Beta Subunit Mink (cluster #1 Of 2), Eukaryotic | Eukaryotes | 700 | 0.41 | Binding ≤ 10μM |
| KCNE1-1-E | Voltage-gated Potassium Channel Beta Subunit Mink (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1200 | 0.39 | Binding ≤ 10μM |
| KCNQ1-1-E | Voltage-gated Potassium Channel Subunit Kv7.1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 700 | 0.41 | Binding ≤ 10μM |
| KCNQ1-1-E | Voltage-gated Potassium Channel Subunit Kv7.1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1200 | 0.39 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KCNE1_HUMAN | P15382 | Voltage-gated Potassium Channel Beta Subunit Mink, Human | 700 | 0.41 | Binding ≤ 1μM |
| KCNQ1_HUMAN | P51787 | Voltage-gated Potassium Channel Subunit Kv7.1, Human | 700 | 0.41 | Binding ≤ 1μM |
| KCNE1_HUMAN | P15382 | Voltage-gated Potassium Channel Beta Subunit Mink, Human | 1200 | 0.39 | Binding ≤ 10μM |
| KCNQ1_HUMAN | P51787 | Voltage-gated Potassium Channel Subunit Kv7.1, Human | 1200 | 0.39 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Voltage gated Potassium channels |
