| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 13th, 2008 | 25 | Yes |
Popular Name: N-[4-[(4-methyl-1-piperidyl)sulfonyl]phenyl]pyridine-2-carboxamide N-[4-[(4-methyl-1-piperidyl)sulf…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.12 | 5.38 | -13.97 | 1 | 6 | 0 | 79 | 359.451 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM4-2-E | Metabotropic Glutamate Receptor 4 (cluster #2 Of 3), Eukaryotic | Eukaryotes | 372 | 0.36 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM4_HUMAN | Q14833 | Metabotropic Glutamate Receptor 4, Human | 372 | 0.36 | Binding ≤ 1μM |
| GRM4_HUMAN | Q14833 | Metabotropic Glutamate Receptor 4, Human | 372 | 0.36 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | |
| G alpha (i) signalling events |
