| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 15th, 2008 | 30 | Yes |
Popular Name: 5-[(Z)-14-(3,5-dihydroxyphenyl)tetradec-7-enyl]benzene-1,3-diol 5-[(Z)-14-(3,5-dihydroxyphenyl)t…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 7.46 | 7.4 | -10.5 | 4 | 4 | 0 | 81 | 412.57 | 14 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DPOLB-3-E | DNA Polymerase Beta (cluster #3 Of 3), Eukaryotic | Eukaryotes | 6500 | 0.24 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DPOLB_RAT | P06766 | DNA Polymerase Beta, Rat | 6500 | 0.24 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Base-free sugar-phosphate removal via the single-nucleotide replacement pathway | |
| Removal of DNA patch containing abasic residue | |
| Resolution of AP sites via the single-nucleotide replacement pathway |
