| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 15th, 2008 | 22 | No |
Popular Name: 2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-4H-chromen-4-one 2-(3,4-Dihydroxyphenyl)-5-hydrox…
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CAS Number: 20243-59-8
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.51 | 1.2 | -13.6 | 3 | 6 | 0 | 100 | 300.266 | 2 | ↓ |
| Hi High (pH 8-9.5) | 2.51 | 2.18 | -57.57 | 2 | 6 | -1 | 103 | 299.258 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PLMN-1-E | Plasminogen (cluster #1 Of 2), Eukaryotic | Eukaryotes | 2300 | 0.36 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PLMN_HUMAN | P00747 | Plasminogen, Human | 2300 | 0.36 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Activation of Matrix Metalloproteinases | |
| Degradation of the extracellular matrix | |
| Dissolution of Fibrin Clot | |
| Platelet degranulation | |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-l | |
| Signaling by PDGF |
No pre-computed analogs available. Try a structural similarity search.