| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 16th, 2008 | 13 | Yes |
Popular Name: (1R,2S,3S,4R,5R)-5-amino-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol (1R,2S,3S,4R,5R)-5-amino-1-(hydr…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -3.61 | -10.86 | -37.53 | 8 | 6 | 1 | 129 | 194.207 | 1 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MGA-1-E | Maltase-glucoamylase (cluster #1 Of 3), Eukaryotic | Eukaryotes | 2200 | 0.61 | Binding ≤ 10μM |
| SUIS-1-E | Sucrase-isomaltase (cluster #1 Of 3), Eukaryotic | Eukaryotes | 49 | 0.79 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SUIS_HUMAN | P14410 | Sucrase-isomaltase, Human | 49 | 0.79 | Binding ≤ 1μM |
| MGA_HUMAN | O43451 | Maltase-glucoamylase, Human | 2200 | 0.61 | Binding ≤ 10μM |
| SUIS_HUMAN | P14410 | Sucrase-isomaltase, Human | 49 | 0.79 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Digestion of dietary carbohydrate |
