| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 21st, 2005 | 22 | Yes |
Popular Name: 2-(4-bromophenyl)-6-chloro-8-methyl-quinoline-4-carboxylic 2-(4-bromophenyl)-6-chloro-8-met…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.48 | -0.05 | -46.75 | 0 | 3 | -1 | 53 | 375.629 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SYEP-1-E | Aminoacyl-tRNA Synthetase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5 | 0.53 | Binding ≤ 10μM |
| SYPC-1-F | Prolyl-tRNA Synthetase (cluster #1 Of 1), Fungal | Fungi | 5 | 0.53 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SYEP_HUMAN | P07814 | Aminoacyl-tRNA Synthetase, Human | 15 | 0.50 | Binding ≤ 1μM |
| SYPC_CANAX | P78600 | Prolyl-tRNA Synthetase, Canax | 5 | 0.53 | Binding ≤ 1μM |
| SYEP_HUMAN | P07814 | Aminoacyl-tRNA Synthetase, Human | 15 | 0.50 | Binding ≤ 10μM |
| SYPC_CANAX | P78600 | Prolyl-tRNA Synthetase, Canax | 5 | 0.53 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Cytosolic tRNA aminoacylation |
