| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 26th, 2005 | 9 | Yes |
Popular Name: 1,4-Dideoxy-1,4-Imino-D-Arabinitol 1,4-Dideoxy-1,4-Imino-D-Arabinitol
Find On: PubMed — Wikipedia — Google
CAS Numbers: 100937-52-8 , [100937-52-8]
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -1.98 | -7.72 | -35.36 | 5 | 4 | 1 | 77 | 134.155 | 1 | ↓ |
| Hi High (pH 8-9.5) | -1.98 | -9.1 | -6.49 | 4 | 4 | 0 | 73 | 133.147 | 1 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| B1WC34-1-E | Alpha-glucosidase II Beta Subunit (cluster #1 Of 1), Eukaryotic | Eukaryotes | 9700 | 0.78 | Binding ≤ 10μM |
| D3ZAN3-1-E | Alpha-glucosidase II (cluster #1 Of 1), Eukaryotic | Eukaryotes | 9700 | 0.78 | Binding ≤ 10μM |
| GDE-1-E | Glycogen Debranching Enzyme (cluster #1 Of 1), Eukaryotic | Eukaryotes | 8400 | 0.79 | Binding ≤ 10μM |
| PYGL-2-E | Liver Glycogen Phosphorylase (cluster #2 Of 2), Eukaryotic | Eukaryotes | 370 | 1.00 | Binding ≤ 10μM |
| PYGM-4-E | Muscle Glycogen Phosphorylase (cluster #4 Of 4), Eukaryotic | Eukaryotes | 396 | 1.00 | Binding ≤ 10μM |
| SUIS-1-E | Sucrase-isomaltase (cluster #1 Of 3), Eukaryotic | Eukaryotes | 5800 | 0.81 | Binding ≤ 10μM |
| AMYG-1-F | Glucoamylase, Intracellular Sporulation-specific (cluster #1 Of 1), Fungal | Fungi | 150 | 1.06 | Binding ≤ 10μM |
| MAL62-2-F | Alpha-glucosidase MAL62 (cluster #2 Of 2), Fungal | Fungi | 840 | 0.95 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MAL62_YEASX | P07265 | Alpha-glucosidase MAL62, Yeasx | 840 | 0.95 | Binding ≤ 1μM |
| AMYG_YEAST | P08019 | Glucoamylase, Intracellular Sporulation-specific, Yeast | 150 | 1.06 | Binding ≤ 1μM |
| PYGM_RABIT | P00489 | Glycogen Phosphorylase, Muscle Form, Rabit | 330 | 1.01 | Binding ≤ 1μM |
| PYGL_RAT | P09811 | Liver Glycogen Phosphorylase, Rat | 370 | 1.00 | Binding ≤ 1μM |
| PYGL_HUMAN | P06737 | Liver Glycogen Phosphorylase, Human | 490 | 0.98 | Binding ≤ 1μM |
| D3ZAN3_RAT | D3ZAN3 | Alpha-glucosidase II, Rat | 9700 | 0.78 | Binding ≤ 10μM |
| B1WC34_RAT | B1WC34 | Alpha-glucosidase II Beta Subunit, Rat | 9700 | 0.78 | Binding ≤ 10μM |
| MAL62_YEASX | P07265 | Alpha-glucosidase MAL62, Yeasx | 840 | 0.95 | Binding ≤ 10μM |
| AMYG_YEAST | P08019 | Glucoamylase, Intracellular Sporulation-specific, Yeast | 150 | 1.06 | Binding ≤ 10μM |
| GDE_HUMAN | P35573 | Glycogen Debranching Enzyme, Human | 8400 | 0.79 | Binding ≤ 10μM |
| PYGM_RABIT | P00489 | Glycogen Phosphorylase, Muscle Form, Rabit | 330 | 1.01 | Binding ≤ 10μM |
| PYGL_RAT | P09811 | Liver Glycogen Phosphorylase, Rat | 370 | 1.00 | Binding ≤ 10μM |
| PYGL_HUMAN | P06737 | Liver Glycogen Phosphorylase, Human | 490 | 0.98 | Binding ≤ 10μM |
| SUIS_RAT | P23739 | Sucrase-isomaltase, Rat | 5800 | 0.81 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Advanced glycosylation endproduct receptor signaling | |
| Amino acid transport across the plasma membrane | |
| Calnexin/calreticulin cycle | |
| Glycogen breakdown (glycogenolysis) | |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
