| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 17th, 2008 | 30 | Yes |
Popular Name: 1-[2-amino-6-(2,3,4,5,6-pentamethylphenyl)pyrido[6,5-d]pyrimidin-7-yl]-3-tert-butyl-urea 1-[2-amino-6-(2,3,4,5,6-pentamet…
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.16 | 10.4 | -18.78 | 4 | 7 | 0 | 106 | 406.534 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FGFR1-1-E | Fibroblast Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1620 | 0.27 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FGFR1_HUMAN | P11362 | Fibroblast Growth Factor Receptor 1, Human | 1620 | 0.27 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Signaling by activated point mutants of FGFR1 | |
| Signaling by FGFR mutants |
