| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 18th, 2008 | 27 | Yes |
Popular Name: 2-[(1S)-5-[3-(2-methoxy-4-methyl-phenoxy)propoxy]indan-1-yl]acetic 2-[(1S)-5-[3-(2-methoxy-4-methyl…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.91 | 10.72 | -53.53 | 0 | 5 | -1 | 68 | 369.437 | 9 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PPARD-1-E | Peroxisome Proliferator-activated Receptor Delta (cluster #1 Of 2), Eukaryotic | Eukaryotes | 8 | 0.42 | Functional ≤ 10μM |
| PPARG-2-E | Peroxisome Proliferator-activated Receptor Gamma (cluster #2 Of 2), Eukaryotic | Eukaryotes | 1670 | 0.30 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PPARD_HUMAN | Q03181 | Peroxisome Proliferator-activated Receptor Delta, Human | 7.5 | 0.42 | Functional ≤ 10μM |
| PPARG_MOUSE | P37238 | Peroxisome Proliferator-activated Receptor Gamma, Mouse | 1670 | 0.30 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Import of palmitoyl-CoA into the mitochondrial matrix | |
| Nuclear Receptor transcription pathway | |
| Regulation of pyruvate dehydrogenase (PDH) complex |
