| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 6th, 2004 | 10 | No |
Popular Name: N-Oxalylglycine N-Oxalylglycine
Find On: PubMed — Wikipedia — Google
CAS Numbers: 5262-39-5 , [5262-39-5]
2-((Carboxymethyl)amino)-2-oxoacetic acid
2-(carboxymethylamino)-2-oxoacetic acid
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -3.00 | -1.85 | -95.16 | 1 | 6 | -2 | 109 | 145.07 | 3 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| Purity | 98% | Matrix Scientific |
| UniProt Database Links | FTO_HUMAN; FTO_MOUSE; FTO_PONAB; FTO_RAT; FXD5A_XENLA; NBL1_XENLA; NBL1_XENTR; NOG1_ARATH; NOG1_ASHGO; NOG1_CAEEL; NOG1_CANGA; NOG1_DICDI; NOG1_DROME; NOG1_ENCCU; NOG1_HUMAN; NOG1_KLULA; NOG1_MOUSE; NOG1_RAT; NOG1_SCHPO; NOG1_TRYBB; NOG1_YEAST; NOGG_HUMAN | ChEBI |
| Warnings | IRRITANT | Matrix Scientific |
| Warnings | Irritant/Refrigerate | Matrix Scientific |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| EGLN1-2-E | Egl Nine Homolog 1 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 8000 | 0.71 | Binding ≤ 10μM |
| EGLN2-2-E | Hypoxia-inducible Factor Prolyl Hydroxylase 1 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 842 | 0.85 | Binding ≤ 10μM |
| P4HA1-2-E | Prolyl 4-hydroxylase Alpha-1 Subunit (cluster #2 Of 2), Eukaryotic | Eukaryotes | 540 | 0.88 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| EGLN2_HUMAN | Q96KS0 | Hypoxia-inducible Factor Prolyl Hydroxylase 1, Human | 842 | 0.85 | Binding ≤ 1μM |
| P4HA1_RAT | P54001 | Prolyl 4-hydroxylase Alpha-1 Subunit, Rat | 540 | 0.88 | Binding ≤ 1μM |
| EGLN1_HUMAN | Q9GZT9 | Egl Nine Homolog 1, Human | 2800 | 0.78 | Binding ≤ 10μM |
| EGLN2_HUMAN | Q96KS0 | Hypoxia-inducible Factor Prolyl Hydroxylase 1, Human | 2100 | 0.79 | Binding ≤ 10μM |
| P4HA1_RAT | P54001 | Prolyl 4-hydroxylase Alpha-1 Subunit, Rat | 2890 | 0.78 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha |
No pre-computed analogs available. Try a structural similarity search.