UCSF

ZINC01541051

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
October 6th, 2004 26 Yes

Popular Name: Fmoc-Leu-OH Fmoc-Leu-OH

Find On: PubMed — Wikipedia — Google

CAS Numbers: 114360-54-2 , 200937-57-1 , 35661-60-0 , [35661-60-0]

Download: MOL2 SDF SMILES Flexibase

Annotations

Vendors

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.53 11.31 -53.21 1 5 -1 78 352.41 7 ↓

Vendor Notes

Note Type Comments Provided By
Melting_Point 152-155? Alfa-Aesar
Melting_Point 152-155° Alfa-Aesar
Mp [°C] 153 - 157 Acros Organics
MP 154 TCI
MP 155°C Indofine
Purity 98% Fluorochem
S phrase S24/25: Avoid contact with skin and eyes. Acros Organics

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
NTR1-1-E Neurotensin Receptor 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 4 0.45 Functional ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
NTR1_HUMAN P30989 Neurotensin Receptor 1, Human 216 0.36 Functional ≤ 10μM

Reactome Annotations from Targets (via Uniprot)

Description Species
G alpha (q) signalling events
Peptide ligand-binding receptors

Analogs ( Draw Identity 99% 90% 80% 70% )