UCSF

ZINC15659837

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Substance Information

In ZINC since Heavy atoms Benign functionality
July 29th, 2008 31 No

Popular Name: (4Z)-1-(3-chlorophenyl)-4-[[5-(4,5-dimethyl-2-nitro-phenyl)-2-furyl]methylene]pyrazolidine-3,5-dione (4Z)-1-(3-chlorophenyl)-4-[[5-(4…

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Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.83 12.64 -18.19 1 8 0 114 437.839 4 ↓

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
FA5-1-E Coagulation Factor V (cluster #1 Of 2), Eukaryotic Eukaryotes 8950 0.23 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
FA5_HUMAN P12259 Coagulation Factor V, Human 7400 0.23 Binding ≤ 10μM

Reactome Annotations from Targets (via Uniprot)

Description Species
Common Pathway
Platelet degranulation

Analogs ( Draw Identity 99% 90% 80% 70% )