| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 7th, 2004 | 15 | No |
Popular Name: DNC009074 DNC009074
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.03 | 1.93 | -10.73 | 0 | 3 | 0 | 43 | 202.209 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DUS1-2-E | Dual Specificity Protein Phosphatase 1 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 820 | 0.57 | Binding ≤ 10μM |
| DUS6-1-E | Dual Specificity Protein Phosphatase 6 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1350 | 0.55 | Binding ≤ 10μM |
| MPIP2-1-E | Dual Specificity Phosphatase Cdc25B (cluster #1 Of 2), Eukaryotic | Eukaryotes | 270 | 0.61 | Binding ≤ 10μM |
| PTPRC-3-E | Leukocyte Common Antigen (cluster #3 Of 3), Eukaryotic | Eukaryotes | 2000 | 0.53 | Binding ≤ 10μM |
| Z81034-2-O | A2780 (Ovarian Carcinoma Cells) (cluster #2 Of 10), Other | Other | 370 | 0.60 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MPIP2_HUMAN | P30305 | Dual Specificity Phosphatase Cdc25B, Human | 270 | 0.61 | Binding ≤ 1μM |
| DUS1_MOUSE | P28563 | Dual Specificity Protein Phosphatase 1, Mouse | 820 | 0.57 | Binding ≤ 1μM |
| MPIP2_HUMAN | P30305 | Dual Specificity Phosphatase Cdc25B, Human | 270 | 0.61 | Binding ≤ 10μM |
| DUS1_MOUSE | P28563 | Dual Specificity Protein Phosphatase 1, Mouse | 820 | 0.57 | Binding ≤ 10μM |
| DUS6_RAT | Q64346 | Dual Specificity Protein Phosphatase 6, Rat | 1350 | 0.55 | Binding ≤ 10μM |
| PTPRC_HUMAN | P08575 | Leukocyte Common Antigen, Human | 2000 | 0.53 | Binding ≤ 10μM |
| Z81034 | Z81034 | A2780 (Ovarian Carcinoma Cells) | 370 | 0.60 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Cyclin A/B1 associated events during G2/M transition | |
| Cyclin A:Cdk2-associated events at S phase entry | |
| Cyclin B2 mediated events | |
| ERKs are inactivated | |
| Other semaphorin interactions | |
| Phosphorylation of CD3 and TCR zeta chains |
