In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
August 19th, 2008 | 38 | Yes |
None
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 2.56 | 13.04 | -45.51 | 5 | 9 | 1 | 123 | 510.622 | 5 | ↓ |
Mid Mid (pH 6-8) | 2.56 | 13.69 | -120.95 | 6 | 9 | 2 | 124 | 511.63 | 5 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CSF1R-1-E | Macrophage Colony-stimulating Factor 1 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 7 | 0.30 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CSF1R_HUMAN | P07333 | Macrophage Colony Stimulating Factor Receptor, Human | 7 | 0.30 | Binding ≤ 1μM |
CSF1R_HUMAN | P07333 | Macrophage Colony Stimulating Factor Receptor, Human | 7 | 0.30 | Binding ≤ 10μM |