UCSF

ZINC00016359

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Substance Information

In ZINC since Heavy atoms Benign functionality
July 23rd, 2004 10 Yes

Popular Name: 5-Vinyluracil 5-Vinyluracil

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CAS Numbers: 37107-81-6 , [37107-81-6]

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.24 -0.03 -13.29 2 4 0 66 138.126 1 ↓

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
DPYD-2-E Dihydropyrimidine Dehydrogenase (cluster #2 Of 2), Eukaryotic Eukaryotes 89 0.99 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
DPYD_HUMAN Q12882 Dihydropyrimidine Dehydrogenase, Human 89 0.99 Binding ≤ 1μM
DPYD_HUMAN Q12882 Dihydropyrimidine Dehydrogenase, Human 89 0.99 Binding ≤ 10μM

Reactome Annotations from Targets (via Uniprot)

Description Species
Pyrimidine catabolism

Analogs ( Draw Identity 99% 90% 80% 70% )