| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 7th, 2004 | 15 | Yes |
Popular Name: 5-(phenylmethyl)-2,4(1h,3h)-pyrimidinedione 5-(phenylmethyl)-2,4(1h,3h)-pyri…
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CAS Number: 18493-83-9
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.04 | -1.88 | -15.15 | 2 | 4 | 0 | 65 | 202.213 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| UPP1-1-E | Uridine Phosphorylase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.56 | Binding ≤ 10μM |
| UPP2-1-E | Uridine Phosphorylase 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.56 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| UPP1_HUMAN | Q16831 | Uridine Phosphorylase 1, Human | 1000 | 0.56 | Binding ≤ 1μM |
| UPP2_HUMAN | O95045 | Uridine Phosphorylase 2, Human | 1000 | 0.56 | Binding ≤ 1μM |
| UPP1_HUMAN | Q16831 | Uridine Phosphorylase 1, Human | 1000 | 0.56 | Binding ≤ 10μM |
| UPP1_MOUSE | P52624 | Uridine Phosphorylase 1, Mouse | 5700 | 0.49 | Binding ≤ 10μM |
| UPP2_HUMAN | O95045 | Uridine Phosphorylase 2, Human | 1000 | 0.56 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Pyrimidine catabolism | |
| Pyrimidine salvage reactions |
No pre-computed analogs available. Try a structural similarity search.