| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 7th, 2004 | 21 | Yes |
Popular Name: 1-((4-methoxyanilino)methyl)-2-naphthol; 6638-24-0; nsc47924 1-((4-methoxyanilino)methyl)-2-n…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.35 | 5.72 | -6.73 | 2 | 3 | 0 | 41 | 279.339 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PHLP2-2-E | PH Domain Leucine-rich Repeat-containing Protein Phosphatase 2 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 4000 | 0.36 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PHLP2_HUMAN | Q6ZVD8 | PH Domain Leucine-rich Repeat-containing Protein Phosphatase 2, Human | 4000 | 0.36 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Negative regulation of the PI3K/AKT network |
