| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 12th, 2008 | 15 | No |
Popular Name: (5Z)-5-[(2-fluorophenyl)methylene]-4-hydroxy-thiazol-2-one (5Z)-5-[(2-fluorophenyl)methylen…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.60 | 3.05 | -7.14 | 1 | 3 | 0 | 50 | 223.228 | 1 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| IGF1R-1-E | Insulin-like Growth Factor 1 Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 6600 | 0.48 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| IGF1R_HUMAN | P08069 | Insulin-like Growth Factor I Receptor, Human | 6600 | 0.48 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| IRS-related events triggered by IGF1R | |
| SHC-related events triggered by IGF1R | |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) |
