| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 15th, 2008 | 14 | Yes |
Popular Name: 5H-Pyrazolo[4,3-g]quinazolin-5-one, 1,6-dihydro- 5H-Pyrazolo[4,3-g]quinazolin-5-o…
Find On: PubMed — Wikipedia — Google
CAS Number: 71785-46-1
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 0.62 | 2.16 | -11.81 | 2 | 5 | 0 | 74 | 186.174 | 0 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MKNK1-1-E | MAP Kinase-interacting Serine/threonine-protein Kinase MNK1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 8170 | 0.51 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MKNK1_HUMAN | Q9BUB5 | MAP Kinase-interacting Serine/threonine-protein Kinase MNK1, Human | 8170 | 0.51 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Spry regulation of FGF signaling |
No pre-computed analogs available. Try a structural similarity search.