| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 9th, 2004 | 23 | No |
Popular Name: A 357300 hydrochloride A 357300 hydrochloride
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CAS Number: 369358-07-6
N'-((2S,3R)-3-AMINO-2-HYDROXY-5-(ISOPROPYLSULFANYL)PENTANOYL)-N-3-CHLOROBENZOYL HYDRAZIDE
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 0.62 | 3.3 | -54.66 | 6 | 6 | 1 | 106 | 360.887 | 8 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| ALOGPS_SOLUBILITY | 4.55e-02 g/l | DrugBank-experimental |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| AMPM2-1-E | Methionine Aminopeptidase 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 110 | 0.42 | Binding ≤ 10μM |
| Z50587-4-O | Homo Sapiens (cluster #4 Of 9), Other | Other | 100 | 0.43 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| AMPM2_HUMAN | P50579 | Methionine Aminopeptidase 2, Human | 110 | 0.42 | Binding ≤ 1μM |
| AMPM2_HUMAN | P50579 | Methionine Aminopeptidase 2, Human | 110 | 0.42 | Binding ≤ 10μM |
| Z50587 | Z50587 | Homo Sapiens | 100 | 0.43 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Inactivation, recovery and regulation of the phototransduction cascade |
No pre-computed analogs available. Try a structural similarity search.