| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 30th, 2008 | 28 | No |
Popular Name: N'-[5-bromo-1-(4-morpholinylmethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]benzohydrazide N'-[5-bromo-1-(4-morpholinylmeth…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.05 | 6.06 | -14 | 1 | 7 | 0 | 76 | 443.301 | 4 | ↓ |
| Ref Reference (pH 7) | 3.05 | 5.92 | -18.47 | 1 | 7 | 0 | 76 | 443.301 | 4 | ↓ |
| Lo Low (pH 4.5-6) | 3.05 | 8.78 | -57.37 | 2 | 7 | 1 | 77 | 444.309 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MET-1-E | Hepatocyte Growth Factor Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3500 | 0.27 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MET_HUMAN | P08581 | Hepatocyte Growth Factor Receptor, Human | 3500 | 0.27 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Sema4D mediated inhibition of cell attachment and migration |
