| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 31st, 2008 | 15 | Yes |
Popular Name: DNC012075 DNC012075
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 0.31 | 1.76 | -39.64 | 3 | 5 | 1 | 64 | 207.257 | 1 | ↓ |
| Mid Mid (pH 6-8) | 0.31 | 1.48 | -13.79 | 2 | 5 | 0 | 62 | 206.249 | 1 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TRPV1-1-E | Vanilloid Receptor (cluster #1 Of 4), Eukaryotic | Eukaryotes | 30 | 0.70 | Functional ≤ 10μM |
| TRPV2-2-E | Transient Receptor Potential Cation Channel Subfamily V Member 2 (cluster #2 Of 3), Eukaryotic | Eukaryotes | 30 | 0.70 | Functional ≤ 10μM |
| TRPV4-2-E | Transient Receptor Potential Cation Channel Subfamily V Member 4 (cluster #2 Of 3), Eukaryotic | Eukaryotes | 30 | 0.70 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TRPV2_RAT | Q9WUD2 | Transient Receptor Potential Cation Channel Subfamily V Member 2, Rat | 30 | 0.70 | Functional ≤ 10μM |
| TRPV4_RAT | Q9ERZ8 | Transient Receptor Potential Cation Channel Subfamily V Member 4, Rat | 30 | 0.70 | Functional ≤ 10μM |
| TRPV1_RAT | O35433 | Vanilloid Receptor, Rat | 30 | 0.70 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| TRP channels |
