| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 23rd, 2004 | 26 | Yes |
Popular Name: (2S)-2-[(1S)-1-phenylethyl]-3-(p-tolyl)-1,2-dihydroquinazolin-4-one (2S)-2-[(1S)-1-phenylethyl]-3-(p…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.77 | 0.86 | -11.7 | 1 | 3 | 0 | 32 | 342.442 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM4-2-E | Metabotropic Glutamate Receptor 4 (cluster #2 Of 3), Eukaryotic | Eukaryotes | 3000 | 0.30 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM4_HUMAN | Q14833 | Metabotropic Glutamate Receptor 4, Human | 3000 | 0.30 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | |
| G alpha (i) signalling events |
