| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 5th, 2008 | 32 | Yes |
Popular Name: Viagra Viagra
Find On: PubMed — Wikipedia — Google
CAS Numbers: 139755-95-6 , 171599-83-0
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.90 | 1.94 | -62.19 | 1 | 10 | -1 | 127 | 459.552 | 7 | ↓ |
| Ref Reference (pH 7) | 2.90 | 1.51 | -53.36 | 1 | 10 | -1 | 127 | 459.552 | 7 | ↓ |
| Mid Mid (pH 6-8) | 2.44 | 3.58 | -18.73 | 2 | 10 | 0 | 124 | 460.56 | 7 | ↓ |
| Mid Mid (pH 6-8) | 2.44 | 3.14 | -14.38 | 2 | 10 | 0 | 124 | 460.56 | 7 | ↓ |
| Lo Low (pH 4.5-6) | 2.44 | 5.93 | -55.46 | 3 | 10 | 1 | 125 | 461.568 | 7 | ↓ |
| Lo Low (pH 4.5-6) | 2.44 | 5.51 | -54.1 | 3 | 10 | 1 | 125 | 461.568 | 7 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| mechanism | Selective inhibitor of cyclic GMP specific phosphodiesterase (Type V) | IBScreen Bioactives |
| biological_use | Used to treat male erectile dysfunction (impotence) and pulmonary arterial hypertension (PAH) | IBScreen Bioactives |
| mechanism | Vasodilator | IBScreen Bioactives IBScreen Bioactives |
No pre-computed analogs available. Try a structural similarity search.