| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 5th, 2008 | 25 | No |
(R)-6-[2-(4-Methoxy-phenyl)-1H-benzoimidazol-5-yl]-4-methyl-4,5-dihydro-2H-pyridazin-3-one
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.44 | 6.03 | -19.6 | 2 | 6 | 0 | 79 | 334.379 | 3 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| mechanism | Partial phosphodiesterase (type III) inhibitor | IBScreen Bioactives |
| biological_use | Shows positive inotropic and vasodilatory activity | IBScreen Bioactives ZereneX Building Blocks |
| biological_use | Used in the treatment of congestive heart failure | IBScreen Bioactives |
| mechanism | Vasodilator | IBScreen Bioactives ZereneX Building Blocks |
