| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 5th, 2008 | 22 | Yes |
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.47 | 7.8 | -33.48 | 2 | 4 | 1 | 35 | 313.45 | 1 | ↓ |
| Mid Mid (pH 6-8) | 3.47 | 7.93 | -9.66 | 1 | 4 | 0 | 35 | 312.442 | 1 | ↓ |
| Mid Mid (pH 6-8) | 3.47 | 9.25 | -41.72 | 2 | 4 | 1 | 36 | 313.45 | 1 | ↓ |
| Lo Low (pH 4.5-6) | -0.57 | 9.74 | -92.69 | 3 | 4 | 2 | 39 | 314.458 | 0 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| mechanism | 5HT(2) and dopamine D2 receptor antagonist | IBScreen Bioactives |
| biological_use | Antipsychotic agent | IBScreen Bioactives IBScreen Bioactives |
| biological_use | Used in the treatment of schizophrenia and bipolar disorder | IBScreen Bioactives |
