| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 5th, 2008 | 23 | Yes |
Popular Name: Succinylsulfathiazole Succinylsulfathiazole
Find On: PubMed — Wikipedia — Google
CAS Number: 116-43-8
116-43-8; Prestwick_1016; Succinylsulfathiazole
4'-(2-Thiazolylsulfamoyl)succinanilic acid
4-oxo-4-{4-[(1,3-thiazol-2-ylamino)sulfonyl]anilino}butanoic acid
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Mid Mid (pH 6-8) | 1.65 | 3.61 | -56.38 | 2 | 8 | -1 | 132 | 354.389 | 6 | ↓ |
| Lo Low (pH 4.5-6) | 1.65 | 1.63 | -20.55 | 3 | 8 | 0 | 129 | 355.397 | 6 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| mechanism | Dihydrofolate reductase inhibitor | ZereneX Building Blocks |
| therap | antibacterial | MicroSource Spectrum |
| biological_use | Antidiarrheic | IBScreen Bioactives |
| Therapy | antimicrobial | SMDC Pharmakon |
| biological_use | Antiseptic | IBScreen Bioactives |
| mechanism | Dihydrofolate reductase inhibitor | IBScreen Bioactives IBScreen Bioactives |
| mechanism | Dihydrofolate synthesis inhibitor | IBScreen Bioactives |
| PUBCHEM_PATENT_ID | EP0199604A2; EP0296854A2; EP0296854B1; EP0315952A2; EP0786999A1; EP0792371A1; EP0815851A2; EP0815851A3; EP0831845A1; EP0831869A1; EP0852494A2; EP0885199A1; EP0888141A1; EP0911039A2; EP0994848A1; EP1021204A2; US4328215; US4665100; US4859575; US4914008; US4 | IBM Patent Data |
| mechanism | Folate antagonist | IBScreen Bioactives |
| biological_use | Intestinal antibacterial agent | IBScreen Bioactives IBScreen Bioactives |
No pre-computed analogs available. Try a structural similarity search.