| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 6th, 2008 | 35 | No |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.53 | 4.65 | -60.35 | 3 | 9 | -1 | 149 | 499.621 | 17 | ↓ |
| Lo Low (pH 4.5-6) | 3.53 | 3.53 | -21.12 | 4 | 9 | 0 | 146 | 500.629 | 17 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| mechanism | Binds to bacterial isoleucyl-tRNA synthetase, which halts the incorporation of isoleucine into bacterial proteins | IBScreen Bioactives |
| biological_use | Broad spectrum antibiotic effective against gram-positive organisms | IBScreen Bioactives |
