In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
November 12th, 2008 | 33 | No |
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | -0.23 | 3.2 | -44.44 | 6 | 10 | 0 | 169 | 457.483 | 3 | ↓ |
Hi High (pH 8-9.5) | -0.23 | 4.09 | -134.56 | 4 | 10 | -2 | 170 | 455.467 | 3 | ↓ |
Mid Mid (pH 6-8) | -0.23 | 3.06 | -52.64 | 5 | 10 | -1 | 167 | 456.475 | 3 | ↓ |
Mid Mid (pH 6-8) | -0.96 | -0.37 | -18.72 | 6 | 10 | 0 | 165 | 457.483 | 2 | ↓ |
Mid Mid (pH 6-8) | -0.96 | 2.91 | -73.2 | 6 | 10 | 0 | 169 | 457.483 | 2 | ↓ |
Mid Mid (pH 6-8) | -0.23 | 3.71 | -75.97 | 5 | 10 | -1 | 171 | 456.475 | 3 | ↓ |
Mid Mid (pH 6-8) | -0.96 | -0.46 | -18.39 | 6 | 10 | 0 | 165 | 457.483 | 2 | ↓ |
Lo Low (pH 4.5-6) | -0.96 | 1.9 | -55.14 | 7 | 10 | 1 | 166 | 458.491 | 2 | ↓ |
Lo Low (pH 4.5-6) | -0.96 | 1.77 | -50.15 | 7 | 10 | 1 | 166 | 458.491 | 2 | ↓ |
Note Type | Comments | Provided By |
---|---|---|
Notes | Cell culture testedMinocycline is a bacteriostatic antibiotic | Apollo Scientific Bioactives |