| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 23rd, 2004 | 23 | Yes |
Popular Name: 1-(6-amino-2,2,4-trimethyl-4-phenyl-3,4-dihydroquinolin-1(2H)-yl)ethanone 1-(6-amino-2,2,4-trimethyl-4-phe…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.36 | 0.75 | -7.3 | 2 | 3 | 0 | 46 | 308.425 | 1 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FSHR-1-E | Follicle Stimulating Hormone Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4400 | 0.33 | Functional ≤ 10μM |
| Z80092-2-O | CHO-K1 (Ovarian Cells) (cluster #2 Of 2), Other | Other | 4400 | 0.33 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z80092 | Z80092 | CHO-K1 (Ovarian Cells) | 4400 | 0.33 | Functional ≤ 10μM |
| FSHR_HUMAN | P23945 | Follicle Stimulating Hormone Receptor, Human | 4400 | 0.33 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (s) signalling events | |
| Hormone ligand-binding receptors |
