In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
November 16th, 2008 | 31 | Yes |
Popular Name: N-[2-(4-ethylpiperazin-1-yl)-4-methyl-6-quinolyl]-2-(3-methylphenoxy)acetamide N-[2-(4-ethylpiperazin-1-yl)-4-m…
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 4.59 | 9.53 | -37.12 | 2 | 6 | 1 | 59 | 419.549 | 6 | ↓ |
Mid Mid (pH 6-8) | 4.59 | 11.58 | -49.79 | 2 | 6 | 1 | 59 | 419.549 | 6 | ↓ |
Mid Mid (pH 6-8) | 4.59 | 9.27 | -20.06 | 1 | 6 | 0 | 58 | 418.541 | 6 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
MCHR1-2-E | Melanin-concentrating Hormone Receptor 1 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 6600 | 0.23 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
MCHR1_HUMAN | Q99705 | Melanin-concentrating Hormone Receptor 1, Human | 6600 | 0.23 | Binding ≤ 10μM |
Description | Species |
---|---|
G alpha (i) signalling events | |
G alpha (q) signalling events | |
Peptide ligand-binding receptors |