UCSF

ZINC20154027

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Substance Information

In ZINC since Heavy atoms Benign functionality
November 17th, 2008 28 Yes

Popular Name: 1-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-3-[4-(trifluoromethyl)phenyl]urea 1-(1,5-dimethyl-3-oxo-2-phenyl-p…

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Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.43 8.15 -30.98 2 6 0 68 390.365 4 ↓

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
FPR2-2-E Lipoxin A4 Receptor (cluster #2 Of 2), Eukaryotic Eukaryotes 100 0.35 Functional ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
FPR2_HUMAN P25090 Lipoxin A4 Receptor, Human 100 0.35 Functional ≤ 10μM

Reactome Annotations from Targets (via Uniprot)

Description Species
Formyl peptide receptors bind formyl peptides and many other ligands
G alpha (i) signalling events
G alpha (q) signalling events

Analogs ( Draw Identity 99% 90% 80% 70% )

No pre-computed analogs available. Try a structural similarity search.