| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 5th, 2005 | 21 | Yes |
Popular Name: 6,7-Dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine 6,7-Dimethoxy-2-(piperazin-1-yl)…
Find On: PubMed — Wikipedia — Google
CAS Numbers: 60547-97-9 , 84050-22-6 , [60547-97-9]
2-Piperazine-4-amino-6,7-dimethoxy quinaoline hydrochloride
2-Piperazine-4-Amino-6,7-Dimethoxy Quinazoline
2-Piperazine-4-amino-6,7-dimethoxy quinoline hydrochloride
2-Piperazine-4-amino-6,7-dimethoxyquinazoline
4-Quinazolinamine, 6,7-dimethoxy-2-(1-piperazinyl)-
6,7-Dimethoxy-2-piperazin-1-yl-quinazolin-4-ylamine
6,7-Dimethoxy-2-piperazin-1-yl-quinazolin-; 4-ylamine
6,7-Dimethoxy-2-piperazino-4-aminoquinazoline
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.02 | -5.49 | -48.25 | 4 | 7 | 1 | 90 | 290.347 | 3 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| Purity | 95% | Fluorochem |
| Purity | 99% | APIChem |
| PUBCHEM_PATENT_ID | WO2000012075A1 | IBM Patent Data |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z104304-1-O | Adrenergic Receptor Alpha-1 (cluster #1 Of 3), Other | Other | 340 | 0.43 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z104304 | Z104304 | Adrenergic Receptor Alpha-1 | 340 | 0.43 | Binding ≤ 1μM |
| Z104304 | Z104304 | Adrenergic Receptor Alpha-1 | 340 | 0.43 | Binding ≤ 10μM |
